Network-Based Inference Framework for Identifying Cancer Genes from Gene Expression Data

Table 1

Significantly enriched GO terms of biological process via BiNGO functional annotation analysis for the 76 intersection genes.

GO term	Hypergeometric test 𝑃 value	Benjamini correction 𝑃-value	Frequency of mapped genes (%)	Fisher 𝑃-value
Immune system process	1.5280𝐸−14	1.7847𝐸−11	33.3	2.3𝐸−12
Cell cycle	3.5350𝐸−12	2.0645𝐸−9	20.4	1.3𝐸−12
Immune response	6.2486𝐸−12	2.4328𝐸−9	24.7	1.3𝐸−9
Cell division	1.5915𝐸−11	4.4740𝐸−9	18.2	1.3𝐸−11
Nuclear division	2.2983𝐸−11	4.4740𝐸−9	16.1	7.2𝐸−12
Apoptotic process	2.2983𝐸−11	4.4740𝐸−9	16.1	7.2𝐸−12
Metabolism	3.9513𝐸−11	5.7689𝐸−9	16.1	1.3𝐸−11
Cell proliferation	1.0537𝐸−10	1.2307𝐸−8	22.5	3.4𝐸−11
Inflammatory response	5.4845𝐸−8	4.2706𝐸−6	41.9	1.4𝐸−10
Response to stimulus	6.6080𝐸−5	1.9433𝐸−3	44.0	5.6𝐸−10
System development	5.1327𝐸−4	8.4436𝐸−3	31.1	2.3𝐸−11