BioMed Research International / 2013 / Article / Tab 4

Research Article

In Vitro Cytotoxicity and In Vivo Acute and Chronic Toxicity of Xanthii Fructus and Its Processed Product

Table 4

Mice grouping, treatments, and responses in acute toxicity testing.

GroupsTreatmentDosage
(g/kg)
MaleFemale
MortalitySymptoms and signsMortalitySymptoms and signs

APhysiological saline00None0None
BWater extraction of XF16.680None0None
CWater extraction of XF166.80Slow respiratory frequency (20%), slow action (20%)0Salivation (20%), piloerection (20%), fast respiratory frequency (20%), slow action (20%)
DWater extraction of XF40080%Vomiting (20%), writhing reaction (20%), fast respiratory frequency (20%), convulsions (20%)80%Pupil dilation (20%), piloerection (20%), convulsions (20%)
EWater extraction of PXF16.680None0None
FWater extraction of PXF166.80Dark hair (20%), salivation (20%)0Convulsions (20%), salivation (20%)
GWater extraction of PXF40040%Convulsions (20%), salivation (20%)40%Convulsions (20%)

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