A Comparison of Synonymous Codon Usage Bias Patterns in DNA and RNA Virus Genomes: Quantifying the Relative Importance of Mutational Pressure and Natural Selection

Figure 2

The relationships between GC content, gene length, and amino acid properties for DNA viruses. (a) GC-gene length relationship without transformation: GC=9.14𝐸−06×genelengths+0.466(𝑅²=0.003,𝑃<0.0001); (b) GC-gene length relationship with log-transformation: log_𝑒(GC)=0.021×log_𝑒(genelengths) − 0.921(𝑅²=0.002,𝑃<0.0001); (c) GC-hydrophobicity relationship: GC=−0.027×GRAVY + 0.484(𝑅²=0.005,𝑃<0.0001); (d) GC-aromaticity relationship: GC=−1.89×AROMO+0.648(𝑅²=0.19,𝑃<0.001).

(a)

(b)

(c)

(d)