A Comparison of Synonymous Codon Usage Bias Patterns in DNA and RNA Virus Genomes: Quantifying the Relative Importance of Mutational Pressure and Natural Selection

Table 1

Correlation analysis of the first two axes of CA and explanatory variables for codon usage bias patterns of virus genomes. For each axis, the correlation coefficients for the top three important variables are marked in boldface.

Variables	DNA viruses				RNA viruses
	CA1	CA2	CCA1	CCA2	CA1	CA2	CCA1	CCA2
T3s	−0.919	−0.158	−0.94	−0.238	−0.774	−0.501	−0.807	−0.57
C3s	0.929	−0.031	0.946	0.052	0.912	0.006	0.945	0.077
A3s	−0.941	0.165	−0.956	0.148	−0.687	0.585	−0.691	0.622
G3s	0.858	0.099	0.899	0.155	0.24	0.203	0.317	0.176
GC3s	0.991	0.022	0.993	0.088	0.935	0.048	0.957	0.088
GC	0.98	−0.13	0.982	−0.104	0.959	−0.094	0.971	−0.041
CAI	0.422	−0.607	0.463	−0.652	0.38	−0.4	0.424	−0.488
ENC	−0.261	−0.056	−0.335	−0.08	0.217	0.051	0.34	0.162
GRAVY	0.028	0.172	0.086	0.169	−0.058	−0.358	−0.158	−0.481
AROMO	−0.328	0.23	−0.368	0.287	−0.362	−0.25	−0.404	−0.306