Research Article

Reduced T Cell Receptor Excision Circle Levels in the Colonic Mucosa of Microscopic Colitis Patients Indicate Local Proliferation rather than Homing of Peripheral Lymphocytes to the Inflamed Mucosa

Table 1

Demographic features of the patients and controls.

Age (years)a at the time Disease duration Bowel movements/dayaOn treatment (total)
Sex (F/M) of disease diagnosis of investigation (years)aNSAIDs PPIs

CC7/161 (46–81)63 (56–84)4 (0–17)5 (3–12) )/ND )2 (8)0 (8)
LC5/069 (60–86)69 (60–86)0 (0–7)6 (6–20) )/ND )0 (5)0 (5)
CC-HR3/049 (42–59)58 (43–63)4 (1–9)4 (2–4)0 (3)0 (3)
LC-HR6/064 (23–79)66 (23–79)1 (0–3)4 (3–6) )/ND )0 (6)0 (6)
NI diarrhoea13/4NA58 (22–77)4 )/ND )NDND
UC2/2NA54 (33–67)10 )/ND )NDND
Controls6/4NA64 (42–88)ND ND

CC: collagenous colitis; LC: lymphocytic colitis; CC-HR: CC-histopathological remission; LC-HR: LC-histopathological remission; NI diarrhoea patients: noninflamed diarrhoea patients; NSAID: nonsteroidal anti-inflammatory drugs, and PPIs: proton pump inhibitors.
aMedian (min–max), ND: no data, NA: not applicable.