Ocular surface reconstruction via the autologous transplantation of tissue-engineered cell sheets fabricated from oral mucosal epithelial cells. Oral mucosal tissue containing whole epithelial cell layers was excised from the oral cavities of the patient. The cells were then seeded onto a temperature-responsive culture dish. The cultured cells were harvested as a cell sheet by reducing the culture temperature. The cells were then transplanted onto the corneal surfaces of the patient.
