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BioMed Research International
Volume 2013, Article ID 434191, 9 pages
Review Article

P.R.L. Platelet Rich Lipotransfert: Our Experience and Current State of Art in the Combined Use of Fat and PRP

1Plastic Surgery Department, Tor Vergata University of San Salvatore, Lauro Place 15, 00186 Rome, Italy
2Anatomic Pathology, Tor Vergata University of Rome, Rome, Italy

Received 5 April 2013; Revised 28 May 2013; Accepted 26 August 2013

Academic Editor: Pedro Cabrales

Copyright © 2013 V. Cervelli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The authors report their experience about the use of P.R.L. PLATELET RICH LIPOTRANSFERT method (platelet rich plasma mixed fat grafting) in 223 patients affected by soft tissue defects (ulcers, Romberg syndrome, Hemifacial atrophy, loss of substance, and signs of aging). This paper introduces the reader to PRP therapy and reviews the current literature on this emerging treatment modality, showing at the current clinical use of PRP in plastic and reconstructive surgery, with description of innovative methods and future prospects. This technique provides a promising alternative to surgery by promoting safe and natural healing. Here recent studies concerning the use of PRP in the treatment of chronic ulcers and soft tissue defect are reviewed.