Research Article

Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

Figure 4

Superposition of the active site structures of the T254A mutant in the internal aldimine form (cyan) and as a gem-diamine complex (orange) with either L-serine (a) or glycine (b).
458571.fig.004a
(a)
458571.fig.004b
(b)