Characterization of Schizophrenia Adverse Drug Interactions through a Network Approach and Drug Classification

Figure 3

Haloperidol and clozapine adverse drug-drug interaction subnetwork extracted from the schizophrenia (SCZ) adverse drug-drug interaction network. Node color corresponds to ATC first-level classification code. With the exception of “NA” for the drugs without ATC classification, the representations of these letters are detailed in Table 2. Nodes with blue labels are SCZ typical drugs, and nodes with black labels are SCZ atypical drugs. Node size corresponds to the number of adverse interactions that the drug had in the SCZ drug-drug interaction network.