Research Article
Characterization of Schizophrenia Adverse Drug Interactions through a Network Approach and Drug Classification
Table 1
Antipsychotics used to treat schizophrenia patients.
| DrugBank ID | Drug name | Number of adverse drug interactions | Typical/atypicala |
| DB01063 | Acetophenazine | 15 | Typical | DB06288 | Amisulpride | 48 | Atypical | DB01238 | Aripiprazole | 12 | Atypical | DB00477 | Chlorpromazine | 51 | Typical | DB01239 | Chlorprothixene | 4 | Typical | DB00363 | Clozapine | 55 | Atypical | DB00875 | Flupenthixol | 20 | Typical | DB00623 | Fluphenazine | 28 | Typical | DB00502 | Haloperidol | 58 | Typical | DB00408 | Loxapine | 20 | Typical | DB00933 | Mesoridazine | 74 | Typical | DB01403 | Methotrimeprazine | 47 | Typical | DB01618 | Molindone | 7 | Atypical | DB00334 | Olanzapine | 10 | Atypical | DB01267 | Paliperidone | 12 | Atypical | DB00850 | Perphenazine | 31 | Typical | DB01100 | Pimozide | 47 | Typical | DB01621 | Pipotiazine | 6 | Typical | DB00433 | Prochlorperazine | 29 | Typical | DB01224 | Quetiapine | 29 | Atypical | DB00734 | Risperidone | 27 | Atypical | DB06144 | Sertindole | 2 | Atypical | DB01622 | Thioproperazine | 3 | Typical | DB00679 | Thioridazine | 86 | Typical | DB01623 | Thiothixene | 96 | Typical | DB00831 | Trifluoperazine | 30 | Typical | DB00246 | Ziprasidone | 90 | Atypical | DB01624 | Zuclopenthixol | 97 | Typical |
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Antipsychotic drugs are classified as typical and atypical mainly based on their different ability to cause extrapyramidal side effects (EPS).
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