Synthesis and Biological Evaluation of O-[3-¹⁸F-fluoropropyl]-α-methyl Tyrosine in Mesothelioma-Bearing Rodents

Table 3

Radiation dose estimates of reference adult for ¹⁸F-FPAMT.

Target organ	rad/mCi	human dose (mCi)	rad
Organs (5 rem annually/15 rem total)
Adrenals	2.98𝐸−03	30	0.089
Brain	9.27𝐸−04	30	0.028
Breasts	1.95𝐸−03	30	0.059
Gall bladder wall	2.88𝐸−03	30	0.086
Lli wall	3.16𝐸−03	30	0.095
Small int.	3.54𝐸−03	30	0.106
Stomach	2.79𝐸−03	30	0.084
Uli wall	3.21𝐸−03	30	0.096
Heart wall	2.94𝐸−03	30	0.088
Kidneys	6.19𝐸−03	30	0.186
Liver	1.51𝐸−03	30	0.045
Lungs	2.40𝐸−03	30	0.072
Muscle	1.63𝐸−03	30	0.049
Pancreas	3.38𝐸−03	30	0.101
Bone surfaces	6.88𝐸−03	30	0.206
Skin	1.55𝐸−03	30	0.047
Testes	2.29𝐸−03	30	0.069
Thymus	2.43𝐸−03	30	0.073
Thyroid	2.47𝐸−03	30	0.074
Urine bladder wall	3.01𝐸−03	30	0.090
Uterus	3.36𝐸−03	30	0.101
Eff dose	2.61𝐸−03	30	0.078
Blood-forming organs (3 rem annually/5 rem total)
Ovaries	3.24𝐸−03	30	0.097
Red marrow	2.29𝐸−03	30	0.069
Spleen	3.42𝐸−03	30	0.103
Eff dose eq.	3.14𝐸−03	30	0.094
Total body	2.35𝐸−03	30	0.071