Preparation, Physicochemical Characterization, and Cell Viability Evaluation of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid

Table 3

Physicochemical and chemical stability of SpHL 20UA1^a.

	Mean diameter; (nm)	Zeta potential; (mV)	UA entrapment; (mg/mL)
Time 0	191.1 ± 6.4^b	1.2 ± 1.4^b	0.77 ± 0.01^b
15 days	210.3 ± 15.2^b	−1.7 ± 3.1^b	0.76 ± 0.01^b
30 days	221.9 ± 25.3^b	−1.6 ± 3.5^b	0.76 ± 0.01^b
60 days	212.7 ± 15.3^b	−1.4 ± 3.6^b	0.77 ± 0.01^b

aEach value represents the mean ± S.D (𝑛=3). ^bThere is no significant difference among the means indicated at the same column (P > 0.05). All means were compared with time zero.