Hydrogen Bond Acceptors and Additional Cationic Charges in Methylene Blue Derivatives: Photophysics and Antimicrobial Efficiency
Figure 6
Photodynamic inactivation of E. coli and S. aureus by MB-3 and MB-4. Photodynamic treatment was performed using different concentrations of MB-3 or MB-4 with and without illumination (30 J cm−2). Surviving colonies were counted 24 h later. Black-dashed line corresponds to a reduction of 3 log10 steps in bacteria numbers (99.9% killing efficacy). White and grey column: controls without illumination. Colored columns: MB-3 + light activation, blue: E. coli; crosshatched: S. aureus. ( experiments: mean values ± standard deviation).
