Figure 3: Effect of NHAG (5 mg/kg) on the average paw oedema in rats induced with arthritis. Each value represents mean paw oedema ± SEM of . The arthritic control group demonstrated a clear evidence of clinical inflammation in both hind paws from day 8 onward. The bonferroni’s post hoc test showed that the paw volume of the arthritic rats was significantly higher than normal control group on day 12 onward (* ). In comparison to the arthritic control group, a significant reduction in paw volume was observed in case of indomethacin (δ ) and NHAG ( ) on days 12 and 16 and continued till end of experiment (*** ) and (** ), respectively.