Association of Atherosclerotic Peripheral Arterial Disease with Adiponectin Genes SNP+45 and SNP+276: A Case-Control Study

Table 5

Comparisons on adiponectin, fetuin-A, and TNF-𝛼 by groups according to SNP+45.

Group	Variable	SNP+45			ANOVA Test
		GG (𝑛=6)	TT (𝑛=175)	TG (𝑛=45)	Stat	P-value
PAD	Adiponectin (pg/mL)	6.17	5.74	5.29	2.352	0.100
	Fetuin-A (µg/mL)	466.33	455.05	496.49	2.004	0.137
	TNF-α (pg/mL)	1.17	1.11	1.25	1.626	0.199
		GG (𝑛=4)	TT (𝑛=93)	TG (𝑛=23)
Non-PAD	Adiponectin (pg/mL)	7.88^a	6.62	6.46^a	4.819	0.010
	Fetuin-A (µg/mL)	344.25	366.45	380.00	0.371	0.691
	TNF-α (pg/mL)	0.89	1.03	1.09	0.374	0.689

PAD: peripheral arterial disease; Stat: statistical parameter of ANOVA test.
aBonferroni test, mean difference = 1.84630, P = 0.015 (adjusted P-value considered statistically significant < 0.0167).