Figure 4: EpiBr administration increases proliferation rate of parasite specific leukocytes from spleen. (a) EpiBr-treated animals showed a tendency to increase spleen weight, with respect to control- and vehicle-treated animals. (b) Spleen leukocytes from EpiBr-treated, vehicle, and control infected hamsters were in vitro cultured in presence of T. solium total antigen. As a consequence of the in vivo exposition to EpiBr, the leukocyte proliferation index in presence of parasitic antigen was augmented by 3.5- and 2.7-fold, compared to immune cells from both control- and vehicle-treated hamsters, respectively. Results are presented as mean +/− standard deviation. ** versus the other groups.