Ovarian and Breast Cancer Spheres Are Similar in Transcriptomic Features and Sensitive to Fenretinide
Figure 4
Identification of CSCs signatures in ovarian and breast cancer cells. Similar procedures were involved to identify changed genes in MCF7 and SUM159 sphere cells. GO (a) and pathways (b) of the changed genes in MCF7 spheres were enriched through DAVID Bioinformatics Resources; the most enriched functions were shown. (c) The number of changed genes was shown. A: ovarian cancer A2780 cells, M: breast cancer MCF7 cells, and S: breast cancer SUM159 cells. (d) The number of enriched transcription factors from the changed genes in A2780, MCF7, and SUM159 spheres cells was analyzed through DAVID Bioinformatics Resources.
