Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues
Figure 2
Organotypic bronchial (a) and nasal (b) models. The in vitro models contained ciliated cells shown in the apical layer of the Hematoxylin and Eosin stained cells (left). The models were cocultured with fibroblasts that are important for the growth and differentiation of epithelial cells (indicated by arrows). Staining of airway lineage markers: p63 and Muc5AC are shown (center and right).
