Research Article

CYP3A5*3 and C3435T MDR1 Polymorphisms in Prognostication of Drug-Resistant Epilepsy in Children and Adolescents

Table 1

Isoforms of CYP 3A5 *3 versus drug resistance of epilepsy.

Isoforms of CYPNumber of patientsControl group [100%]
Drug resistant [100%]Drug responsive [100%]

1.3.10 (21.7%)8 (28.6%)22 (31.0%)
3.3.36 (78.3%)20 (71.4%)49 (69.0%)
Comparison of groups of patients with epilepsy NS ( )
Comparisons with control groupNS ( )NS ( )
Hardy-Weinberg equilibriumMaintained ( )Maintained ( )

NS: not statistically significant.