Research Article

CYP3A5*3 and C3435T MDR1 Polymorphisms in Prognostication of Drug-Resistant Epilepsy in Children and Adolescents

Table 3

Cooccurrence of genotypes CYP3A5 and C3435T MDR1 and drug resistance in epilepsy.

Cooccurrence of CYP3A5 versus MDR1Number of patientsComparison group
Drug resistant [100%]Drug sensitive [100%]

1.3 versus CC00NS
1.3 versus CT17.7%22.2%
1.3 versus TT5.9%0
3.3 versus CC17.7%0
3.3 versus CT52.8%44.4%
3.3 versus TT5.9%33.4%

NS: not statistically significant.