Research Article
CYP3A5*3 and C3435T MDR1 Polymorphisms in Prognostication of Drug-Resistant Epilepsy in Children and Adolescents
Table 3
Cooccurrence of genotypes CYP3A5 and C3435T MDR1 and drug resistance in epilepsy.
| Cooccurrence of CYP3A5 versus MDR1 | Number of patients | Comparison group | Drug resistant [100%] | Drug sensitive [100%] |
| 1.3 versus CC | 0 | 0 | NS |
1.3 versus CT | 17.7% | 22.2% | 1.3 versus TT | 5.9% | 0 | 3.3 versus CC | 17.7% | 0 | 3.3 versus CT | 52.8% | 44.4% | 3.3 versus TT | 5.9% | 33.4% |
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NS: not statistically significant.
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