Recovery of Fertility in Azoospermia Rats after Injection of Adipose-Tissue-Derived Mesenchymal Stem Cells: The Sperm Generation

Figure 4

Cell transplantation into rete testis and morphological analyses of testes after 12 weeks. 1 × 10⁶ cells were mixed with toluidine blue (1 : 1, v/v), and the mixture was injected into the rete testis of the left testicle of rats (a–c). The right testicle of rats was left untreated after busulfan (d). After 12 weeks, the atrophy in right testicles (f) was significant, when compared with the left testicles with rAT-MSCs treatment (e). There were significant differences in both volume and weight of testicles: 𝑃=0.0074 and 𝑃=0.0015, respectively (g).

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