BioMed Research International / 2013 / Article / Tab 2

Research Article

Essential Oil of Common Sage (Salvia officinalis L.) from Jordan: Assessment of Safety in Mammalian Cells and Its Antifungal and Anti-Inflammatory Potential

Table 2

Antifungal activity (MIC and MLC) of Salvia officinalis essential oil from Jordan against Candida, dermatophyte, and Aspergillus strains.

StrainsS1S2FluconazoleAmphotericin B
MICaMLCaMICaMLCaMICbMLCbMICbMLCb

Candida albicans ATCC 102312.552.551>128N.T.N.T.
C. tropicalis ATCC 1380355554>128N.T.N.T.
C. krusei H9552.556464–128N.T.N.T.
C. guillermondii MAT232.52.51.25–2.51.25–2.588N.T.N.T.
C. parapsilosis ATCC 9001851055<1<1N.T.N.T.
Cryptococcus neoformans CECT 10781.251.250.64–1.251.25–2.516128N.T.N.T.
Epidermophyton floccosum FF90.640.64–1.250.64–1.250.64–1.251616N.T.N.T.
Microsporum canis FF11.252.51.251.25128128N.T.N.T.
M. gypseum CECT 29051.25–2.51.25–2.51.252.5128>128N.T.N.T.
Trichophyton mentagrophytes FF71.251.251.251.2516–3232–64N.T.N.T.
T. mentagrophytes var. interdigitale CECT 29581.252.51.252.5128≥128N.T.N.T.
T. rubrum CECT 27940.641.250.640.64–1.251664N.T.N.T.
T. verrucosum CECT 29922.52.51.25–2.52.5>128>128N.T.N.T.
Aspergillus niger ATCC 164045>205>10N.T.N.T.28
A. fumigatus ATCC 466452.5–5>205>10N.T.N.T.24
A. flavus F4410>205>10N.T.N.T.1-24

Results were obtained from 3 independent experiments performed in duplicate.
aMIC and MLC were determined by a macrodilution method and expressed in μL/mL (V/V).
bMIC and MLC were determined by a macrodilution method and expressed in μg/mL (W/V).
N.T.: not tested.