Topical Application of Ketoprofen Improves Gait Disturbance in Rat Models of Acute Inflammation

Figure 2

Comparison of the therapeutic effects of topical NSAID formulations in an acute inflammation model. Effects of topical NSAID formulations on gait disturbance (a) and hind paw edema (b) in a 𝛾-carrageenan-treated inflammation model. Each column represents the mean±SE of 6–18 animals. Asterisks show a significant difference from control, ^∗𝑃<0.05, ^∗∗𝑃<0.01. Hyperalgesia in yeast-treated inflammation model (c). Each column represents the mean ± SE of 10–20 animals. Asterisks show a significant difference from control, ^∗𝑃<0.05, ^∗∗𝑃<0.01.

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