Development of a Generic Microfluidic Device for Simultaneous Detection of Antibodies and Nucleic Acids in Oral Fluids
Rheonix processor platform (controller) and CARD technologies. (A) Controller box with integrated vacuum and pressure pump system. A manifold forms the interface between the controller box and the CARD; in the magnified top view the heating module and the solenoid connections (ports) are indicated. Vacuum and pressure ballast tanks are integrated within the controller box. (B (a)) panel showing a minimal schematic of the basic 3-layer PS CARD structure with 2 small and one larger diaphragm (valves/pumps); (B (b)) a top down view of the 3-layer laminated structure shown in panel (B (a)) (without any reservoirs mounted). (C) Diagram showing the valve operations required for peristaltic fluid movement in the CARD.