Table 4: Acetaminophen assay [mg · tablet−1] obtained from ten repeated different analyses by TLC-densitometric and UV-spectrodensitometric methods for tablets of three different pharmaceutical manufactures.

No.Product 1Product 2Product 3
Assay
by TLC-densitometric method
Assay
by UV-spectrophotometric method
Assay
by TLC-densitometric method
Assay
by UV-spectrophotometric method
Assay
by TLC-densitometric method
Assay
by UV-spectrophotometric method

1500.3502.3509.0504.5502.4505.7
2503.5491.3488.1497.5496.8489.8
3488.3486.5499.6494.7509.6511.2
4495.2494.4504.4498.6497.8492.3
5500.5493.5494.3503.6502.7508.9
6491.8490.6499.6489.9505.8506.7
7489.1494.5499.2497.3497.6491.2
8504.2506.2501.5501.9509.8505.9
9503.1506.9496.9492.9506.7497.9
10491.2490.8498.8493.9508.9504.6
Average assay496.7495.7499.1497.5503.8501.4
Label claimed500.0500.0500.0500.0500.0500.0
Standard deviation (SD)6.47.05.64.85.17.9
Coefficient of variation CV, % 1.271.401.120.961.011.58

TLC-densitometric method compared with UV-spectrophotometric method
t-test
t calculated0.340.690.81
tabulated 2.102.102.10
F-test
F calculated1.241.362.39
tabulated 3.183.183.18