Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2013, Article ID 564534, 11 pages
http://dx.doi.org/10.1155/2013/564534
Review Article

Neuroprotective Function of 14-3-3 Proteins in Neurodegeneration

1Neural Plasticity Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan
2Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada H3A 2B4

Received 26 August 2013; Accepted 17 October 2013

Academic Editor: Anna Maria Lavezzi

Copyright © 2013 Tadayuki Shimada et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [46 citations]

The following is the list of published articles that have cited the current article.

  • Adika Putra Pangestu, Dono Indarto, and Balgis, “Neuroglobin activator In Silico found from Mirabilis Jalapa for stroke treatment,” vol. 2021, pp. 070002, . View at Publisher · View at Google Scholar
  • Katharina Bell, Corina Wilding, Sebastian Funke, Norbert Pfeiffer, and Franz H. Grus, “Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway,” BMC Ophthalmology, vol. 15, no. 1, 2015. View at Publisher · View at Google Scholar
  • Andrew Kaplan, Stephan Ong Tone, and Alyson E. Fournier, “Extrinsic and intrinsic regulation of axon regeneration at a crossroads,” Frontiers in Molecular Neuroscience, vol. 8, no. June, 2015. View at Publisher · View at Google Scholar
  • Aline Teichmann, Daiani M. Vargas, Karina M. Monteiro, Bruna V. Meneghetti, Cristine S. Dutra, Rodolfo Paredes, Norbel Galanti, Arnaldo Zaha, and Henrique B. Ferreira, “ Characterization of 14-3-3 Isoforms Expressed in the Echinococcus granulosus Pathogenic Larval Stage ,” Journal of Proteome Research, pp. 150320125637007, 2015. View at Publisher · View at Google Scholar
  • Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, and Shogo Matsuyama, “The influence of chronic ibuprofen treatment on proteins expressed in the mouse hippocampus,” European Journal of Pharmacology, 2015. View at Publisher · View at Google Scholar
  • Ying Pang, Chao Rui Chai, Kai Gao, Xi Hua Jia, Jin Ge Kong, Xiao Qian Chen, Greg Vatcher, Jian Guo Chen, and Albert Cheung Hoi Yu, “Ischemia preconditioning protects astrocytes from ischemic injury through 14-3-3,” Journal Of Neuroscience Research, vol. 93, no. 10, pp. 1507–1518, 2015. View at Publisher · View at Google Scholar
  • Jae Wook Hyeon, Su Yeon Kim, Jeongmin Lee, Jun Sun Park, Kyu Jam Hwang, Sol Moe Lee, SeongSoo A. An, Myung Koo Lee, and Young Ran Ju, “Alternative application of Tau protein in Creutzfeldt-Jakob disease diagnosis: Improvement for weakly positive 14-3-3 protein in the laboratory,” Scientific Reports, vol. 5, pp. 15283, 2015. View at Publisher · View at Google Scholar
  • De-Hyung Lee, Petra Steinacker, Silvia Seubert, Tanja Turnescu, Arthur Melms, Arndt Manzel, Markus Otto, and Ralf A. Linker, “Role of glial 14-3-3 gamma protein in autoimmune demyelination,” Journal of Neuroinflammation, vol. 12, no. 1, 2015. View at Publisher · View at Google Scholar
  • Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, and Shogo Matsuyama, “The influence of chronic nicotine treatment on proteins expressed in the mouse hippocampus and cortex,” European Journal Of Pharmacology, vol. 780, pp. 16–25, 2016. View at Publisher · View at Google Scholar
  • Divya Elizabeth Mathew, Kaitlyn Larsen, Paulina Janeczek, and Joanne M. Lewohl, “Expression of 14-3-3 transcript isoforms in response to ethanol exposure and their regulation by miRNAs,” Molecular and Cellular Neuroscience, 2016. View at Publisher · View at Google Scholar
  • Takahiko Umahara, Toshiki Uchihara, Noriyuki Shibata, Ayako Nakamura, and Haruo Hanyu, “14-3-3 eta isoform colocalizes TDP-43 on the coarse granules in the anterior horn cells of patients with sporadic amyotrophic lateral sclerosis,” Brain Research, 2016. View at Publisher · View at Google Scholar
  • Micha Feld, Richard Garcia, Jörg Buddenkotte, Shintaro Katayama, Katherine Lewis, Gareth Muirhead, Peter Hevezi, Kristin Plesser, Holger Schrumpf, Kaarel Krjutskov, Olga Sergeeva, Hans Werner Müller, Sophia Tsoka, Juha Kere, Stacey R. Dillon, Martin Steinhoff, and Bernhard Homey, “The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves,” Journal of Allergy and Clinical Immunology, 2016. View at Publisher · View at Google Scholar
  • M.J. Leitão, I. Baldeiras, M.R. Almeida, M.H. Ribeiro, A.C. Santos, M. Ribeiro, J. Tomás, S. Rocha, I. Santana, and C.R. Oliveira, “Sporadic Creutzfeldt–Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3γ assay,” Neuroscience, 2016. View at Publisher · View at Google Scholar
  • Franc Llorens, Matthias Schmitz, Isidro Ferrer, and Inga Zerr, “CSF biomarkers in neurodegenerative and vascular dementias,” Progress in Neurobiology, 2016. View at Publisher · View at Google Scholar
  • Shraddha Mehta, Sreelakshmi Sreenivasamurthy, Shefali Banerjee, Sandeepan Mukherjee, Keshava Prasad, and Abhay Chowdhary, “Pathway Analysis of Proteomics Profiles in Rabies Infection: Towards Future Biomarkers?,” OMICS: A Journal of Integrative Biology, vol. 20, no. 2, pp. 97–109, 2016. View at Publisher · View at Google Scholar
  • Martin Mueller, Byron Oppliger, Marianne Joerger-Messerli, Ursula Reinhart, Eytan Barnea, Michael Paidas, Boris W. Kramer, Daniel V. Surbek, and Andreina Schoeberlein, “Wharton's Jelly Mesenchymal Stem Cells Protect the Immature Brain in Rats and Modulate Cell Fate,” Stem Cells and Development, 2016. View at Publisher · View at Google Scholar
  • Serggio Lanata, and Michael D. Geschwindpp. 350–364, 2016. View at Publisher · View at Google Scholar
  • Juncal Fernández-Orth, Petra Ehling, Tobias Ruck, Susann Pankratz, Majella-Sophie Hofmann, Peter Landgraf, Daniela C. Dieterich, Karl-Heinz Smalla, Thilo Kähne, Guiscard Seebohm, Thomas Budde, Heinz Wiendl, Stefan Bittner, and Sven G. Meuth, “ 14-3-3 Proteins regulate K 2P 5.1 surface expression on T lymphocytes ,” Traffic, vol. 18, no. 1, pp. 29–43, 2016. View at Publisher · View at Google Scholar
  • Srinivas Ayyadevara, Samuel G. Mackintosh, Alan J. Tackett, Meenakshisundaram Balasubramaniam, Pooja Suri, Dennis H. Sullivan, Robert J. Shmookler Reis, and Richard A. Dennis, “Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans,” Aging, vol. 8, no. 12, pp. 3486–3497, 2016. View at Publisher · View at Google Scholar
  • Jeong-Ho Park, Yeong-Gon Choi, Yun-Jung Lee, Seok-Joo Park, Hong-Seok Choi, Kyung-Chan Choi, Eun-Kyoung Choi, and Yong-Sun Kim, “Real-Time Quaking-Induced Conversion Analysis for the Diagnosis of Sporadic Creutzfeldt-Jakob Disease in Korea,” Journal of Clinical Neurology, vol. 12, no. 1, pp. 101, 2016. View at Publisher · View at Google Scholar
  • Jin Hui Zhang, Ying Li, Xuan Bo Song, Xiao Hong Ji, Hong Na Sun, Hui Wang, Song Bin Fu, Li Jun Zhao, and Dian Jun Sun, “Differential expression of serum proteins in rats subchronically exposed to arsenic identified by iTRAQ-based proteomic technology—14-3-3 ζ protein to serve as a potential biomarker,” Toxicol. Res., vol. 5, no. 2, pp. 651–659, 2016. View at Publisher · View at Google Scholar
  • Ju-Hwang Park, Hae Rim Jang, In Young Lee, Hye Kyung Oh, Seongman Kang, Eui-Ju Choi, and Hyangshuk Rhim, “Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment,” Human Molecular Genetics, vol. 26, no. 18, pp. 3615–3629, 2017. View at Publisher · View at Google Scholar
  • Danyal Smani, Sumit Sarkar, James Raymick, Jyotshna Kanungo, Merle G. Paule, and Qiang Gu, “Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model,” Molecular Neurobiology, 2017. View at Publisher · View at Google Scholar
  • Nammi Park, Boah Lee, Tae Hwan Kim, Ajung Kim, Eun Mi Hwang, Jae Cheal Yoo, Gwan-su Yi, Jae-Yong Park, Abdullateef Nashed, Young-Sun Lee, and Da Yong Lee, “14-3-3γ regulates Copine1-mediated neuronal differentiation in HiB5 hippocampal progenitor cells,” Experimental Cell Research, vol. 356, no. 1, pp. 85–92, 2017. View at Publisher · View at Google Scholar
  • A. Fourier, A. Dorey, A. Perret-Liaudet, and I. Quadrio, “Detection of CSF 14-3-3 Protein in Sporadic Creutzfeldt-Jakob Disease Patients Using a New Automated Capillary Western Assay,” Molecular Neurobiology, 2017. View at Publisher · View at Google Scholar
  • Loes M. Stevers, Richard G. Doveston, Lech-Gustav Milroy, Rens M. J. M. De Vries, Luc Brunsveld, and Christian Ottmann, “Structural interface between LRRK2 and 14-3-3 protein,” Biochemical Journal, vol. 474, no. 7, pp. 1273–1287, 2017. View at Publisher · View at Google Scholar
  • Andrew Kaplan, Barbara Morquette, Antje Kroner, SooYuen Leong, Carolin Madwar, Ricardo Sanz, Sara L. Banerjee, Jack Antel, Nicolas Bisson, Samuel David, and Alyson E. Fournier, “Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration,” Neuron, vol. 93, no. 5, pp. 1082–1093.e5, 2017. View at Publisher · View at Google Scholar
  • Henry C. H. Law, Samuel S. W. Szeto, Quan Quan, Yun Zhao, Zaijun Zhang, Olga Krakovska, Leong Ting Lui, Chengyou Zheng, Simon M.-Y. Lee, K. W. Michael Siu, Yuqiang Wang, and Ivan K. Chu, “Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia,” Journal of Proteome Research, 2017. View at Publisher · View at Google Scholar
  • Andrew Kaplan, Mardja Bueno, and Alyson E. Fournier, “Extracellular functions of 14-3-3 adaptor proteins,” Cellular Signalling, vol. 31, pp. 26–30, 2017. View at Publisher · View at Google Scholar
  • Soo-Jin Oh, Junsung Woo, Young-Sun Lee, Minhee Cho, Eunju Kim, Nam-Chul Cho, Jae-Yong Park, Ae Nim Pae, C. Justin Lee, and Eun Mi Hwang, “Direct interaction with 14–3-3γ promotes surface expression of Best1 channel in astrocyte,” Molecular Brain, vol. 10, no. 1, 2017. View at Publisher · View at Google Scholar
  • Yakovlev, and Gulyaeva, “Molecular partners of Cortexin in the brain,” Neurochemical Journal, vol. 11, no. 1, pp. 115–119, 2017. View at Publisher · View at Google Scholar
  • Danielle Gushue, Allen Herbst, Valerie Sim, Debbie McKenzie, and Judd M. Aiken, “14-3-3 and enolase abundances in the CSF of Prion diseased rats,” Prion, pp. 1–8, 2018. View at Publisher · View at Google Scholar
  • Alice Ballone, Federica Centorrino, and Christian Ottmann, “14-3-3: A Case Study in PPI Modulation,” Molecules, vol. 23, no. 6, pp. 1386, 2018. View at Publisher · View at Google Scholar
  • Sebastian A. Andrei, Femke A. Meijer, João Filipe Neves, Luc Brunsveld, Isabelle Landrieu, Christian Ottmann, and Lech-Gustav Milroy, “Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes,” ACS Chemical Neuroscience, 2018. View at Publisher · View at Google Scholar
  • Kaori Wakabayashi, Takahiko Umahara, Katsuiku Hirokawa, Haruo Hanyu, and Toshiki Uchihara, “14-3-3 protein sigma isoform co-localizes with phosphorylated α-synuclein in Lewy bodies and Lewy neurites in patients with Lewy body disease,” Neuroscience Letters, 2018. View at Publisher · View at Google Scholar
  • Betul Karademir, Gulce Sari, Ayse Tarbin Jannuzzi, Sravani Musunuri, Grzegorz Wicher, Tilman Grune, Jia Mi, Husniye Hacioglu-Bay, Karin Forsberg-Nilsson, Jonas Bergquist, and Tobias Jung, “Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib,” Scientific Reports, vol. 8, no. 1, 2018. View at Publisher · View at Google Scholar
  • Sangyun Kim, Eva Bagyinszky, Vo Van Giau, Young Chul Youn, and Seong Soo A. An, “Characterization of mutations in prnp (PRION) gene and their possible roles in neurodegenerative diseases,” Neuropsychiatric Disease and Treatment, vol. 14, pp. 2067–2085, 2018. View at Publisher · View at Google Scholar
  • Qiang Gu, Elvis Cuevas, James Raymick, Jyotshna Kanungo, and Sumit Sarkar, “Downregulation of 14-3-3 Proteins in Alzheimer’s Disease,” Molecular Neurobiology, 2019. View at Publisher · View at Google Scholar
  • Xiaolan Fan, Lang Cui, Yao Zeng, Wenhao Song, Uma Gaur, and Mingyao Yang, “14-3-3 Proteins Are on the Crossroads of Cancer, Aging, and Age-Related Neurodegenerative Disease,” International Journal of Molecular Sciences, vol. 20, no. 14, pp. 3518, 2019. View at Publisher · View at Google Scholar
  • Nazila Momendoust, Jamal Moshtaghian, Fariba Esmaeili, Fariba Dehghanian, and Veronica Dumit, “Induction of Tyrosine Hydroxylase Gene Expression in Embryonal Carcinoma Stem Cells Using a Natural Tissue‐Specific Inducer,” Developmental Neurobiology, vol. 79, no. 6, pp. 559–577, 2019. View at Publisher · View at Google Scholar
  • Shang-Jun Yin, Jae-Rin Lee, Hyunchang Kwak, Bit-Na Lee, Ji-Won Han, Myong-Joon Hahn, Yong-Doo Park, and Jun-Mo Yang, “Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: Microarray integrating bioinformatics approaches,” Journal of Biomolecular Structure and Dynamics, pp. 1–17, 2019. View at Publisher · View at Google Scholar
  • Yuwen Chen, Xingyu Chen, Zhiyang Yao, Yuqi Shi, Junwen Xiong, Jingjing Zhou, Zhengding Su, and Yongqi Huang, “14-3-3/Tau Interaction and Tau Amyloidogenesis,” Journal of Molecular Neuroscience, 2019. View at Publisher · View at Google Scholar
  • Gincy George, V.P. Snijesh, Sowmya Bekshe Lokappa, and Jobin Varkey, “Construction of Parkinson's disease marker-based weighted protein-protein interaction network for prioritization of co-expressed genes,” Gene, 2019. View at Publisher · View at Google Scholar
  • Melissa K. Jones, Bin Lu, Dawn Zhaohui Chen, Weston R. Spivia, Augustus T. Mercado, Alexander V. Ljubimov, Clive N. Svendsen, Jennifer E. Van Eyk, and Shaomei Wang, “In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival,” Proteomics, pp. 1800213, 2019. View at Publisher · View at Google Scholar
  • 明松 石, “Screening of 14-3-3? Natural Product Inhibitors by Molecular Docking,” Journal of Advances in Physical Chemistry, vol. 08, no. 01, pp. 11–21, 2019. View at Publisher · View at Google Scholar
  • Do Eon Kim, Chang-Hoon Cho, Kyoung Mi Sim, Osung Kwon, Eun Mi Hwang, Hyung-Wook Kim, and Jae-Yong Park, “14-3-3γ Haploinsufficient Mice Display Hyperactive and Stress-sensitive Behaviors,” Experimental Neurobiology, vol. 28, no. 1, pp. 43, 2019. View at Publisher · View at Google Scholar