Hippocampal Gene Expression of Deiodinases 2 and 3 and Effects of 3,5-Diiodo-L-Thyronine T2 in Mouse Depression Paradigms
Figure 5
3,5-Diiodo-L-thyronine T2-treated mice display unaltered anxiety-like and locomotor behaviour. In the dark-light box, mice that were treated with T2 at the dose 750 mcg/kg or 1500 mcg/kg did not differ from vehicle-treated mice in (a) the time spent in the lit compartment, (b) latency of exit in the lit area, and (c) number of exits to the lit box. (d) In the novel cage, mice that received T2 at the dose 750 mcg/kg or 1500 mcg/kg did not differ from vehicle-treated mice in number of rearings. All groups constituted 9 mice.
