Sensitivity of Rabbit Ventricular Action Potential and Ca2+ Dynamics to Small Variations in Membrane Currents and Ion Diffusion Coefficients
Table 3
Diffusion coefficients varied in the model.
Definition
Symbol
Baseline value
1
Diffusion coefficient for Ca2+ from junctional cleft to SL compartment
1.64 10−6 cm2/s
2
Diffusion coefficient for Ca2+ from SL compartment to bulk cytosol
1.22 10−6 cm2/s
3
Diffusion coefficient for Na+ from junctional cleft to SL compartment
1.09 10−5 cm2/s
4
Diffusion coefficient for Na+ from SL compartment to bulk cytosol
1.79 10−6 cm2/s
Notes: in the Shannon et al. article [1] corresponds to , to , to , and to . The baseline diffusion coefficients values used in this study are the same as in [1].
