Cordyceps sinensis Increases Hypoxia Tolerance by Inducing Heme Oxygenase-1 and Metallothionein via Nrf2 Activation in Human Lung Epithelial Cells
Figure 3
Cytoprotective effects of aqueous extract of Cordyceps sinensis in A549 cells exposed to different oxygen percentages (0.1, 0.5%, 1%, or 5% O2; (a)–(d) for 48 h. Cells exposed to hypoxia showed cell death (dark gray bar) in comparison to unexposed cells (black bar) which was dependent on oxygen percentage. Treatment of cells with aqueous extract of Cordyceps sinensis increased cell survival following hypoxia exposure and the efficacy of extract was dose dependent (light gray bars). *.
