Cordyceps sinensis Increases Hypoxia Tolerance by Inducing Heme Oxygenase-1 and Metallothionein via Nrf2 Activation in Human Lung Epithelial Cells
Figure 6
Effect of Cordyceps sinensis treatment on the expression of antioxidant transcription factor (Nrf2; (a)) and its regulated genes heme oxygenase-1 (HO1; (b)) and metallothionein 1 (MT; (c)) in A549 cells (0.5% O2) hypoxia exposure for 48 h. There was a significant increase in Nrf2, HO1, and MT levels following hypoxia exposure and also in the presence of Cordyceps sinensis extract. The figures are representative of three independent experiments. These were normalized with actin to observe any change in expression.
