Cordyceps sinensis Increases Hypoxia Tolerance by Inducing Heme Oxygenase-1 and Metallothionein via Nrf2 Activation in Human Lung Epithelial Cells
Figure 7
Western blot analyses showed significant increase in NFκB (a) and pro-inflammatory cytokines TNFα (b) while no change was observed in levels of anti-inflammatory cytokines TGFβ (c) in A549 cells following hypoxia (0.5% O2) exposure for 48 h. The treatment of cells with extract prevented increase in NFκB and TNFα levels following hypoxia exposure. Further, an increase in TGFβ levels was also evident in Cordyceps sinensis treated cells. The figures are representative of three independent experiments. These were normalized with β-actin (d) to observe any change in expression.
