Higher Plasma Pyridoxal Phosphate Is Associated with Increased Antioxidant Enzyme Activities in Critically Ill Surgical Patients

Table 3

Partial Pearson correlations of plasma pyridoxal-5′-phosphate with homocysteine, indicators of oxidative stress, and antioxidant capacities in the surgical intensive care unit¹.

	Plasma PLP (nmol/L) (𝑛=37)
	Day 1	Day 7	Δ (Day 7 − Day 1)^2
		𝑟
Erythrocyte PLP (pmol/g Hb)
Day 1	0.39*
Day 7		0.37^†
Δ (Day 7 − Day 1)			0.01
Plasma PLP/Erythrocyte PLP ratio
Day 1	0.44**
Day 7		0.48**
Δ (Day 7 − Day 1)			0.58**
Plasma homocysteine (𝜇mol/L)
Day 1	−0.10
Day 7		0.33
Δ (Day 7 − Day 1)			0.33
MDA (𝜇mol/L)
Day 1	−0.19
Day 7		0.13
Δ (Day 7 − Day 1)			0.10
Total antioxidant capacity (𝜇mol/L)
Day 1	−0.10
Day 7		0.36^†
Δ (Day 7 − Day 1)			0.08
SOD (U/mL)
Day 1	0.42*
Day 7		0.37*
Δ (Day 7 − Day 1)			0.56**
GST (nmol/min/mL)
Day 1	−0.09
Day 7		−0.05
Δ (Day 7 − Day 1)			−0.06
GPx (nmol/min/mL)
Day 1	−0.06
Day 7		0.05
Δ (Day 7 − Day 1)			0.27

1Values are presented as correlation coefficient (𝑟) by using partial Pearson correlation coefficient after adjusting age, gender, and C-reactive protein. PLP: pyridoxal-5′-phosphate; Hb: hemoglobin; MDA: malondialdehyde; SOD: superoxide dismutase; GST: glutathione S-transferase; GPx: glutathione peroxidase.
²Δ (Day 7 − Day 1) is the value of the difference between day 7 and day 1.
* 𝑃<0.05; **𝑃<0.01; ^†𝑃<0.06.