Chitosan Combined with Poly-L-arginine as Efficient, Safe, and Serum-Insensitive Vehicle with RNase Protection Ability for siRNA Delivery

<table>RNase stability of siRNA in the CS/PLA/siRNA complexes. Naked siRNA was a negative control. The complexes were incubated with RNase A (5 mIU/<i>µ</i>g siRNA) at 37°C for 6 h. The reaction was inactivated at 70°C and was released by SDS. The remaining siRNA was analyzed by agarose gel electrophoresis.</table>

BioMed Research International

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Figure 6

Figure 6: Chitosan Combined with Poly-L-arginine as Efficient, Safe, and Serum-Insensitive Vehicle with RNase Protection Ability for siRNA Delivery 