Tuning Aerosol Particle Size Distribution of Metered Dose Inhalers Using Cosolvents and Surfactants

Table 2

Composition of HFA 227 formulations maintaining constant Pluronic L81 and fluorescein Na concentrations (𝑛=3).

Formulation	Pluronic L81 (% w/w)	Ethanol (% w/w)	Fluorescein Na (% w/w)
5% w/w EtOH	5	5	0.04
10% w/w EtOH	5	10	0.04
13% w/w EtOH	5	13	0.04
15% w/w EtOH	5	15	0.04