Advances in the Applications of Polyhydroxyalkanoate Nanoparticles for Novel Drug Delivery System
Figure 3
Schematic presentation of PHB granule formation within the cytoplasm of PHB producing microorganism. PHB is synthesized by polymerization of (R)-3-hydroxybutyryl-CoA molecules by PHB synthase leading to the formation of PHB granules. PHB inclusions consist of a hydrophobic core of amorphous PHB surrounded by phospholipid and various proteins.