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BioMed Research International
Volume 2013, Article ID 582957, 5 pages
Research Article

Seroprevalence of St. Louis Encephalitis Virus and West Nile Virus (Flavivirus, Flaviviridae) in Horses, Uruguay

1Sección Virología, Facultad de Ciencias, Universidad de la República, 11400 Montevideo, Uruguay
2Laboratorio de Arbovirus, Instituto de Virología Dr. J. M. Vanella, Universidad Nacional de Córdoba, 5016 Córdoba, Argentina
3Instituto de Investigaciones Biológicas y Tecnológicas CONICET-FCEFyN, UNC, 5016 Córdoba, Argentina

Received 30 April 2013; Accepted 1 October 2013

Academic Editor: Vittorio Sambri

Copyright © 2013 Analía Burgueño et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) belong to the Japanese encephalitis antigenic complex (Flavivirus genus, Flaviviridae family). They show antigenic close relationships and share many similarities in their ecology. Both are responsible for serious human diseases. The aim of this study was to investigate the presence of neutralizing antibodies to these viruses in horses from Uruguay. To do this, 425 horse sera were collected in 2007 and analyzed by plaque reduction neutralization tests. As a result, 205 sera (48.2%) were found positive for SLEV, with titers ranging between 10 and 80. Two sera remained inconclusive, since they showed low titers to WNV and SLEV (10 and 20), not allowing us to demonstrate activity of WNV in our territory. This is the first report of circulation of SLEV in horses in Uruguay.