BioMed Research International

Research Article

Association of Apolipoprotein A5 Gene 1131T C Polymorphism with the Risk of Metabolic Syndrome in Korean Subjects

Table 2

Association of the APOA5 −1131T>C polymorphism with MS parameters in the study population.
　VariablesTT/TC/CCSlope (95% CI) value
Total
(2901)		Number (%)1404 (48.40)/1237 (42.64)/260 (8.96)——
Age (years) ——
SBP (mm Hg) 0.589 (−0.244, 1.422)0.166
DBP (mm Hg) 0.326 (−0.282, 0.934)0.264
WC (cm) 0.051 (−0.451, 0.553)0.843
FBG (mg/dL) −0.013 (−1.505, 1.479)0.987
LogTG (mg/dL) 0.056 (0.044, 0.069)
HDL-C (mg/dL) −1.700 (−2.368, −1.031)
MS
(1004)		Number (%)452 (15.58)/429 (14.79)/123 (4.24)——
Age (years) ——
SBP (mm Hg) 0.185 (−1.218, 1.587)0.796
DBP (mm Hg) 0.065 (−0.941, 1.071)0.899
WC (cm) −0.328 (−1.018, 0.362)0.351
FBG (mg/dL) 1.103 (−4.389, 2.182)0.510
LogTG (mg/dL) 0.046 (0.028, 0.065)
HDL-C (mg/dL) −0.818 (−1.566, −0.071)0.032
Control
(1897)		Number (%)952 (32.82)/808 (27.85)/137 (4.72)——
Age (years) ——
SBP (mm Hg) −0.223 (−1.15, 0.704)0.637
DBP (mm Hg) −0.205 (−0.907, 0.497)0.566
WC (cm) −0.519 (−1.098, 0.06)0.079
FBG (mg/dL) −0.822 (−2.067, 0.424)0.196
LogTG (mg/dL) 0.042 (0.029, 0.055)
HDL-C (mg/dL) −1.304 (−2.174, −0.435)0.003
Values are indicated as the mean ± standard deviation.
value: multiple regression analysis adjusted for age and sex (TT, TC, CC).
Abbreviations: CI: confidence interval; SBP: systolic blood pressure; DBP: diastolic blood pressure; WC: waist circumference; FBG: fasting blood glucose; LogTG: log-transformed triglyceride; HDL-C: high-density lipoprotein cholesterol.
Bold indicates statistical significance ( ).