Association of Apolipoprotein A5 Gene −1131T>C Polymorphism with the Risk of Metabolic Syndrome in Korean Subjects

Table 3

The prevalence of MS risk factors according to APOA5 −1131 genotype.

	Variables	Number (%)				𝑃 value
		TT (1404)	TC (1237)	CC (260)	Total (2901)
Total; (2901)	High FBG	423 (30.13)	398 (32.17)	96 (36.92)	917 (31.61)	0.082
	Low HDL-C	674 (48.01)	639 (51.66)	156 (60.00)	1469 (50.64)	0.001
	High BP	448 (31.91)	411 (33.23)	110 (42.31)	969 (33.40)	0.005
	High TG	312 (22.22)	345 (27.89)	106 (40.77)	763 (26.30)	𝟖.𝟔𝟑𝟕𝐄−𝟏𝟎
	Large WC	720 (51.28)	604 (48.83)	135 (51.92)	1459 (50.29)	0.389
Male; (1040)	High FBG	178 (37.55)	155 (33.55)	44 (42.31)	377 (36.25)	0.142
	Low HDL-C	177 (37.34)	204 (44.16)	52 (50.00)	433 (41.63)	0.001
	High BP	181 (38.19)	189 (40.91)	46 (44.23)	416 (40.00)	0.059
	High TG	141 (29.75)	158 (34.20)	49 (47.12)	348 (33.46)	𝟏.𝟕𝟏𝟖𝐄−𝟎𝟒
	Large WC	170 (35.86)	157 (33.98)	44 (42.31)	371 (35.67)	0.101
Female (1861)	High FBG	245 (26.34)	243 (31.35)	52 (33.33)	540 (29.02)	0.294
	Low HDL-C	497 (53.44)	435 (56.13)	104 (66.67)	1036 (55.67)	0.316
	High BP	267 (28.71)	222 (28.65)	64 (41.03)	553 (29.72)	0.045
	High TG	171 (18.39)	187 (24.13)	57 (36.54)	415 (22.30)	𝟏.𝟏𝟒𝟔𝐄−𝟎𝟒
	Large WC	550 (59.14)	447 (57.68)	91 (58.33)	1088 (58.46)	0.187

Values are indicated as number (%).
𝑃 value: test for difference of proportions (TT, TC, CC).
Abbreviations: MS: metabolic syndrome; FBG: fasting blood glucose; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride; WC: waist circumference.
Bold indicates statistical significance (𝑃<0.05).