Figure 3: Effect of andrographolide on liver tissue morphology in hyperlipidemia rats. (a) No fat droplets were found in the liver of normal control group; (b) many large fat droplets were indicated by the arrowheads in the liver of rats challenged orally with P. gingivalis; (c) lower accumulation of lipid droplets shown in hepatic tissue of treatment group with 20 mg/kg andrographolide (H&E staining, 20x).