Figure 4: A 55-year-old female had partial mastectomy 5 years ago due to intraductal carcinoma in situ in right breast with yearly mammographic follow up. (a) Digital mammogram showed microcalcifications (arrow) with segmental distribution over the lower-inner quarter of the left breast. The BIRADS score was rated as 0 by two readers and 4A by one reader. (b) Tomosynthesis revealed the microcalcifications being inside the dilated tubular structure, which was toward the nipple. The BIRADS score was upgraded to 4B by one reader and 4C by two readers. The lesion was proved pathologically to be an invasive cancer (T1cN0M0).