Serum Proteome Analysis in Patients with Rheumatoid Arthritis Receiving Therapy with Tocilizumab: An Anti-Interleukin-6 Receptor Antibody

Table 1

Profiles of the patients with RA.

No.	Age (years)	Sex	Duration of RA (years)	Class/stage^†	DAS28-ESR			PSL (mg/day)	MTX (mg/week)
					0	4W	8W
1	57	F	18	2/4	5.01	3.16	2.93	2.5	6
2	93	F	11	2/4	5.32	3.52	3.00	3	6
3	91	F	20	1/2	3.65	2.38	2.66	2	6
4	51	F	—	2/3	5.82	2.13	2.06	5	5
5	55	F	21	2/4	4.62	2.66	3.27	0	2
6	68	F	9	1/4	4.05	4.05	1.66	4	0
7	63	F	27	3/4	4.93	3.63	2.98	5	4

†: Functional (class) and radiological (stage) classifications by Steinbrocker et al. [11].
DAS28: disease activity score 28 [12]. The DAS28 was evaluated at the time of serum collection. 0: before the first treatment, 4W: before the 2nd treatment, 8W: before the 3rd treatment.
PSL: dose of prednisolone, MTX: dose of methotrexate.