Alkaline Phosphatase: The Next Independent Predictor of the Poor 90-Day Outcome in Alcoholic Hepatitis

Table 1

Baseline characteristics of the study population^#.

	Total group (𝑛=116)		Survivors (𝑛=95)		Nonsurvivors (𝑛=21)
	Mean	SD	Mean	SD	Mean	SD
Age/years	49.35	10.66	49.32	10.66	49.50	10.95
Tbil*** mg/dL	9.13	6.78	8.04	5.37	14.31	9.95
Alb*** g/dL	3.02	0.54	3.14	0.49	2.49	0.44
INR***	1.47	0.41	1.41	0.34	1.80	0.53
PT*** s	16.61	4.29	15.86	3.63	20.17	5.37
Crea mg/dL	1.10	0.94	1.07	1.02	1.21	0.38
Na** mEq/L	136.25	5.01	136.85	4.62	133.40	5.88
ALT U/L	73.30	64.63	74.43	69.06	67.95	37.82
AST U/L	155.36	105.06	155.76	112.14	153.50	63.33
AP** U/L	179.68	102.39	168.54	92.79	235.35	130.48
GGT U/L	927.00	1279.59	1007.80	1374.00	494.47	307.53
WBC* ×10^3/𝜇L	10.17	6.39	9.58	5.96	12.93	7.70
Hgb g/dL	11.50	1.87	11.57	1.98	11.17	1.25
RBC ×10^6/𝜇L	3.46	0.65	3.50	0.66	3.25	0.56
PLT ×10^3/𝜇L	147.28	85.39	148.03	87.70	143.70	75.38
CRP* mg/L	39.20	52.16	34.32	50.31	61.42	55.94
Gender M/F	72/44		61/34		11/10
Ascites*** (+/−)	74/42		53/42		21/0
HE** (+/−)	29/87		18/77		11/10
CS** response (+/−)	29/12		20/2		9/10

^∗∗∗𝑃<0.001; ^∗∗𝑃<0.01; ^∗𝑃<0.05 variables significantly different in nonsurvivors versus survivors; ^#Alb: albumin (NR 3.2–4.8); ALT: alanine aminotransferase (normal range (NR) <31); AP: alkaline phosphatase (NR 45–129); AST: aspartate aminotransferase (NR <34); CS: corticosteroids; Crea: creatinine (NR 0.5–1.1); CRP: C-reactive protein (NR 0.0–5.0); F: female; GGT: gamma-glutamyl transpeptidase (NR <50.0); HE: hepatic encephalopathy; Hgb: hemoglobin (NR 14.0–18.0); INR: International Normalized Ratio (NR 0.8–1.2); M: male; Na: sodium (NR 136–145); PLT: platelets (NR 130–400); PT: prothrombin time (NR 10.4–13.0); q25: first quartile; q75: third quartile, RBC: red blood cells (NR 4.5–6.1); SD: standard deviation, Tbil: total bilirubin (NR 0.3–1.2); WBC: white blood cells (NR 4.8–10.8).