Research Article
Modulation of Pineal Melatonin Synthesis by Glutamate Involves Paracrine Interactions between Pinealocytes and Astrocytes through NF-B Activation
Table 1
Summary of intracellular [Ca2+] changes in astrocytes and pinealocytes after stimulation.
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Intracellular [Ca2+] in fluo-4-loaded astrocytes and pinealocytes was measured as described in Section 2. The majority of the stimulated cells responded with an increase in intracellular [Ca2+] after the addition of either glutamate (600 μM), ionotropic glutamatergic agonists (AMPA 50 μM and NMDA 100 μM), or a class I metabotropic glutamatergic agonist (DHPG 50 μM). |