Development of Microencapsulation Delivery System for Long-Term Preservation of Probiotics as Biotherapeutics Agent

Table 11

Advantages and disadvantages of coacervation technique.

Advantages	Disadvantages
(i) The advantages are high payload (99%) and controls the release of core material [146]	(i) The disadvantages are high cost of the particle isolation procedure and complexity of technique
(ii) The process can be carried out at room temperature making it particularly suitable for heat sensitive probiotic bacteria [26]	(ii) But it was suggested that the optimization of the last step and use of spray dryer instead of fluidized or freeze dryer can reduce the overall cost [146]