Pharmacodynamic Analysis of Magnetic Resonance Imaging-Monitored Focused Ultrasound-Induced Blood-Brain Barrier Opening for Drug Delivery to Brain Tumors
Figure 5
(a)–(c) R1 change as a function of time before and after FUS exposure for normal animals, 10-day and 17-day tumor animals. (d–f) The corresponding R1 accumulation as a function of time over 80 minutes for (a)–(c).