Modulation of the Rat Hepatic Cytochrome P4501A Subfamily Using Biotin Supplementation
Figure 3
Effects of biotin treatment on EROD and MROD levels in the hepatic tissues of rats that were treated with a single i.p. dose of PBS 1X (control), biotin (2 mg/kg), BaP (10 mg/kg), or biotin + BaP (2 mg/kg of biotin plus 10 mg/kg of BaP). EROD activity: (pmol of resorufin formed/min/mg of protein); MROD activity: (pmol of resorufin formed/min/mg of protein). The results represent the means ± SEM. rats per group. A was considered to be significantly different from the control group using Student’s t-test.
