Figure 5: miR-27b, miR-122, and miR-328a levels after 1, 3, 5, and 7 days of biotin treatment (2 mg/kg, i.p.) in rat liver. The data are expressed as fold changes relative to the control (defined as 1, dashed line). The data represent the means ± SEM of 4 rats per group from two independent experiments. *Significantly different from the controls ( ), as assessed using Student’s t-test.