Anti-Actin IgA Antibodies Identify Celiac Disease Patients with a Marsh 3 Intestinal Damage among Subjects with Moderate Anti-TG2 Levels

Figure 1

Distribution of CD patients and controls according to algorithm-1 in the retrospective study. For each of the 3 Subgroups, the degree of intestinal atrophy is also illustrated. CD: coeliac disease; anti-TG2: anti-transglutaminase type 2 antibody; ULN: upper limit of normal; EMA: anti-endomysial antibodies; HLA: human leukocyte antigen; 3a, 3b, 3c, 2, 1, and 0 indicate the grade of intestinal damage according to the Marsh-Oberhuber classification [13, 14]; OEGDB: oesophagogastroduodenoscopy and biopsy; and AAA-IgA: anti-actin IgA antibody.