Anti-Actin IgA Antibodies Identify Celiac Disease Patients with a Marsh 3 Intestinal Damage among Subjects with Moderate Anti-TG2 Levels

Figure 2

AAA-IgA measurement in subjects of Subgroup 2 with anti-TG2 levels comprised between 4 and 10 times ULN. Distribution of AAA-IgA in the 36 subjects of Subgroup 2 with anti-TG2 levels comprised between 4 and 10 times ULN. CD: coeliac disease; anti-TG2: anti-transglutaminase type 2 antibody; ULN: upper limit of normal; EMA: anti-endomysial antibodies; HLA: human leukocyte antigen; 3a, 3b, 3c, 2, 1, and 0 indicate the grade of intestinal damage according to the Marsh-Oberhuber classification [13, 14]; OEGDB: oesophagogastroduodenoscopy and biopsy; and AAA-IgA: anti-actin IgA antibody.