BioMed Research International / 2013 / Article / Tab 2

Research Article

PSCA and Oct-4 Expression in the Benign and Malignant Lesions of Gallbladder: Implication for Carcinogenesis, Progression, and Prognosis of Gallbladder Adenocarcinoma

Table 2

The association of PSCA and Oct-4 expression with the clinicopathological characteristics of gallbladder adenocarcinoma.

Clinicopathological characteristicsTotal no.PSCAOct-4
Pos. nos. (%) Pos. nos. (%)

Sex
 Male3116 (51.6)0.16>0.0517 (54.8)0.01>0.05
 Female7743 (55.8)43 (55.8)
Age (years)
 ≤452414 (58.3)0.17>0.0516 (66.7)1.54>0.05
 >458445 (53.6)44 (52.4)
Differentiation*
 Well3614 (38.8)15.12<0.0113 (36.1)13.31<0.05
 Moderately3116 (51.6)18 (58.1)
 Poorly3025 (83.3) 24 (80.0)
 Mucinous A.114 (36.4)5 (45.5)
Tumor size (cm)
 <2 cm3112 (38.7)4.47<0.0510 (32.3)9.56<0.01
 ≥2 cm7747 (61.0)50 (64.9)
Lymph node metastasis
 No4919 (38.8)8.04<0.0119 (38.8)10.23<0.01
 Yes5940 (67.8)41 (69.5)
T stages
 T1145 (35.7)7.73<0.054 (28.6)17.24<0.01
 T23515 (42.9)13 (37.1)
 T33723 (62.2)25 (67.6)
 T42216 (72.7) 18 (81.8)
Gallstones
 No5027 (54.0)0.01>0.0528 (56.0)0.01>0.05
 Yes5832 (55.2)32 (55.2)

Comparison between well-differentiated and moderately differentiated adenocarcinomas: = 1.09, ; = 3.23, .
*Comparison between wel-differentiated and poorly differentiated adenocarcinomas: = 7.29, ; = 6.98, < 0.01.
*Comparison between moderately differentiated and poorly differentiated adenocarcinoma: = 6.96, ; = 3.42, .
Mucinous A.: mucinous adenocarcinoma.